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KMID : 0043320090320101373
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Archives of Pharmacal Research
2009 Volume.32 No. 10 p.1373 ~ p.1377
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Phenylpropanoid Glycosides from Heterosmilax erythrantha and Their Antioxidant Activity
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Kim Young-Ho
Nhiem Nguyen Xuan
Kiem Phan Van
Minh Chau Van
Ban Ninh Khac
Cuong Nguyen Xuan
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Abstract
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By various chromatographic methods, one new phenylpropanoid glycoside, heterosmilaside(1), two known phenylpropanoid glycosides, helonioside B (2), and 2’,6’-diacetyl-3,6-diferuloyl sucrose (3), and three known flavonoids, isoquercetin (4), quercetin-3-O-β-D-glucuronopyranoside (5), and quercetin-3-O-(2’’-α-L-rhamnopyranosyl)-β-D-glucuronopyranoside (6) were isolated from the methanolic extract of the aerial part of Heterosmilax erythrantha Baill. Their structures were elucidated on the basis of spectroscopic analyses. All the isolated compounds were tested for antioxidant activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay. Among them, compounds 5 and 6 showed significant antioxidant activity with SC50 values of 3.7 and 6.5 μg/mL, respectively.
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KEYWORD
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Heterosmilax erythrantha, Smilacaeae, Heterosmilaside, Antioxidant activity
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